T. Schwarze, M. Mertens, P. Müller, J. Riemer, P. Wessig, H.-J. Holdt
Highly K+-Selective Fluorescent Probes for Lifetime Sensing of Kalium-Ionen in Living Cells
Chemistry - A European Jornal 2017, 23, 17186
DOI: 10.1002/chem.201703799
Coupling of K+ selective N-(o-isopropoxy)phenylaza-18-crown-6 with [1,3]dioxolo[4,5-f][1,3]benzo-dioxole ester fluorophore yields a new fluorescent probe for the sensing of Kalium-Ionen by increasing the averaged fluorescence decay time. This fluorescent tool is a good candidate for a reliable analysis of physiologically relevant K+ levels by fluorescence lifetime imaging microscopy (FLIM) in vivo.(Cover Profile)
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