B. Schmidt, M. Riemer, M. Karras
2,2'-Biphenols via protecting group free thermal or microwave accelerated Suzuki-Miyaura coupling in water
J. Org. Chem. 2013, 78, 0
DOI: 10.1021/jo401398n
2,2'-Biphenols are ubiquitious in nature. In this publication, a convenient protocol for their synthesis is described which uses a Suzuki-Miyaura cross coupling in water, catalyzed by Palladium on charcoal. No protecting groups are required, and less reactive aryl bromides undergo the cross coupling under microwave conditions.
Zurück zur Übersicht »