Schultze, C.; Foß, S.; Schmidt, B.
8-Prenylflavanones via Microwave Promoted Tandem Claisen Rearrangement/6-endo-trig Cyclization and Cross Metathesis
Eur. J. Org. Chem. 2020, 7373-7384
DOI: 10.1002/ejoc.202001378
A microwave-promoted one-pot Claisen-rearrangement / 6-endo-trig cyclization yields allylflavanones, which undergo selective cross metathesis reactions with 2-methyl-2-butene to furnish prenylated flavanone natural products. One example is maximaflavanone, a secondary metabolite isolated from the Indian medicinal plant Tephrosia maxima.
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