Publikation

Riemer, N.; Riemer, M.; Krüger, M.; Clarkson, G. J.; Shipman, M.; Schmidt, B.
Synthesis of Arylidene-β-lactams via exo-Selective Matsuda-Heck Arylation of Methylene-β-lactams.
J.Org.Chem. 2021, 86, 8786-8796
DOI: 10.1021/acs.joc.1c00638
Exo-methylene beta-lactams, which are sensitive to ring opening under conventional (cross)-coupling conditions, undergo a Pd-catalyzed arylation at ambient temperature in high yields and selectivity. This work resulted from an international collaboration with researchers at the University of Warwick, UK.
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