Publikation

M. Klaper, T. Linker
Intramolecular Transfer of Singlet Oxygen
J. Am. Chem. Soc. 2015, 137, 13744­
DOI: 10.1021/jacs.5b07848
The intramolecular transfer of energy (FRET) and electrons (Dexter) are of great interest for the scientific community and well understood. On the other hand, the intramolecular transfer of singlet oxygen (1O2), a reactive and short-lived oxygen species, has been hitherto unknown. This process would be very interesting, since 1O2 plays an important role in the photodynamic therapy (PDT). Herein, we present the first successful intramolecular transfer of 1O2 from a donor to an acceptor. Furthermore, we found a dependence of conformation and temperature comparable with FRET. We provide several pieces of evidence for the intramolecular character of this transfer, including competition experiments. Our studies should be interesting not only from the theoretical and mechanistic point of view, but should offer the basis for the design of new 1O2 donors and applications in PDT.
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